UPF3A 抗体
Quick Overview for UPF3A 抗体 (ABIN7120628)
抗原
See all UPF3A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- UPF3A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- UPF3 regulator of nonsense transcripts homolog A(yeast)
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亚型
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 327-476) antibody
UPF3A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 274-374) antibodyUPF3A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 1-443) antibodyUPF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 382-475) antibodyUPF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 359-408) antibodyUPF3A 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IHC:1:20-1:200,IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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别名
- UPF3A
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背景
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Synonyms: Regulator of nonsense transcripts 3A|Nonsense mRNA reducing factor 3A|Up-frameshift suppressor 3 homolog A (hUpf3)|UPF3A|RENT3A|UPF3
Background: Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.
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分子量
- 51 kDa
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基因ID
- 65110
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UniProt
- Q9H1J1
抗原
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